Imagine being able to predict to know at birth or even before birth, our risk of cancer, risk of dementia, of heart disease, of different genetic diseases, at a stage where we might be able to do something about them even before they occur. That’s going to be a whole paradigm shift in medicine. This is possible with the potential of gene sequencing, however, the way in which DNA sequencing is done today is inefficient. It costs about 5 thousand dollars, takes a couple months and overall the process isn’t effective. That’s why I decided to apply my knowledge of nanotechnology to solve this problem. At Genis, we are leveraging silicon nitride nanopores to sequence DNA 10x more effectively than current methods. Knowing that each nucleotide gives off a different current, we have the DNA passing through the nanopore with an electrical current within the pore. We measure the change in current and find the sequence from that. We have simulated this using visual molecular dynamics and have seen positive simulation results. Now we are talking with different universities for support and lab access so we can start fabricating it in labs!
What inspired you (or your team)?
After diving deeper into my passion, I realized that the potential of the genome is incredible! I really wanted everyone to have access to this data to ensure longer healthier lives but with the current processes out there, this was not possible. I wanted to change this and therefore, started Genis.